Ameco Research Analyst imply that the global market for Liquid Nitrogen Cryopreservation will achieve USD 4,530 Million by 2028 with a CAGR of more than 12% throughout the predicted years
The preservation of cells is a critical component of cell culture. Animal cells can only be preserved by freezing them, which can be done with liquid nitrogen or cryogenic freezers. Slowly lowering the temperature of prepared cells to -30 to -60°C, then transferring them to temperatures below -130°C, is the freezing process. The cells become physiologically inert at ultralow temperatures and can be stored for years. Liquid nitrogen storage allows for the absolute consistency of the lowest feasible storage temperature, but it necessitates the use of enormous quantities (depth) of liquid nitrogen, which is a potential hazard. Cross-contamination by virus pathogens via the liquid nitrogen media has also been demonstrated. Because of these factors, vapor phase nitrogen is most typically used for ultra-low temperature storage.
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Market Dynamics
An increasing number of government initiatives for the preservation of stem cells is one of the primary factors driving the growth of the global liquid nitrogen cryopreservation market. The National Cord Blood Program (NCBP), which was founded in 1992, investigates cord blood as a possible treatment for critical public health issues. This is used to determine the best hemopoetic transplants for patients who do not have a bone marrow donor match.
Liquid nitrogen is a cryogenic liquid that is frequently used in research labs. It is an exceptionally cold material since "cryogenic" that means "associated to very low temperature." When liquefied under high pressure, it can expand to a large amount of gas. This generic chemical safety guidance explains how to handle this compound safely in research laboratories. Standard operating procedures (SOPs) for the purchasing, storage, and safe handling of this chemical that are particular to the PI's research are developed and implemented by the principal investigator (PI) or the lab manager. When liquid nitrogen vaporizes, it expands 695 times its original volume and has no odor or color. As a result, if adequate liquid nitrogen is dispersed to reduce the oxygen percentage below 19.5 percent, an oxygen deficit could occur, resulting in unconsciousness. If there is a severe lack of oxygen, death may result. Handlers must ensure that the room is adequately ventilated while using cryogens inside to minimise asphyxiation concerns.
Every year, the capacity to replace organs and tissues on demand saves and improves the lives of millions of people around the world, resulting in public health benefits by curing a variety of life-threatening conditions. Advanced organ preservation procedures may even allow for cutting-edge pretransplant therapies such as immunomodulation or gene therapy approaches for functional augmentation in specialist laboratories, which have the potential to improve transplant results. As a result of these reasons, the liquid nitrogen cryopreservation industry has seen strong growth, contributing to the worldwide market's overall expansion.
Global Liquid Nitrogen Cryopreservation Market Segmentation
The liquid nitrogen cryopreservation market is divided into three categories application, end-use, and regions. The application segment can be categorized into stem cells, embryos & oocytes, sperms, semen & testicular tissues, and others. Among them, the stem cells segment accumulated the most important market share in 2020. Cryopreservatives are required ingredients in stem cell concentrates because they prevent the production of intracellular and extracellular crystals, which leads to cell death. The usual cryoprotectant is DMSO, which protects living cells from freezing damage. It was first employed in medicine as an anti-inflammatory reagent, and it is still utilized in auto-immune illnesses on occasion.
By end-use segment, the market is categorized into academic and research institutes, stem cell banks, biotechnology and pharmaceutical organization, stem cell research laboratories, and contract research organization. The stem cell laboratories segment acquired the maximum share of the market in 2020.
Regional Stance
North America, Latin America, Asia-Pacific, Europe, and the Middle East & Africa (MEA) are the regional categorization of the worldwide liquid nitrogen cryopreservation market. Europe recorded the leading share in 2020. This might be linked to the region's rising contract research organizations (CRO), and contract manufacturing organizations, and growing research & development activities. Meanwhile, the Asia-Pacific region is likely to achieve the fastest CAGR throughout the forecast period 2021 – 2028. In response to the escalating COVID-19, countries including South Korea, India, Russia, and others are focusing on strengthening their R&D skills and investing in the development and establishment of advanced laboratories.
Major Players
The top players offered in the report include Abeyance Cryo Solutions, Antech Group Inc., BIOLOGIX GROUP LTD, CUSTOM BIOGENIC SYSTEMS, Chart Industries, Taylor-Wharton, Linde, Thermo Fisher Scientific, Inc., and Worthington Industries, Inc.
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